subject: Sudies of Lupus. Metformin and the glucose metabolism inhibitor 2-deoxy-d-glucose (2DG), restoration of the defective interleukin-2 (IL-2) production by TC CD4+ T cells
object_opposite: Decreased Interferon Gamma production, Lupus chmistry diminished
misc: normalized T cell metabolism and reversed disease biomarkers. excessive IFN-γ production was significantly reduced by metformin in vitro diminished
author_year: Yiming Yin1, Seung-Chul Choi1, Zhiwei Xu1, Daniel J. Perry1, Howard Seay1, Byron P. Croker1, Eric S. Sobel Todd M. Brusko1 Laurence Morel1,/ 2015
journal_volume_page: sci Translational Med/11/274 pg.274
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